Gilead reinforces their commitment to gynecologic health

At Gilead, we recognize the significance of gynecologic health and are actively supporting and enhancing efforts in this field. Through our extensive research and clinical trials, we aim to better understand, prevent, and treat endometrial, cervical, and ovarian cancers. Our commitment to clinical trials ensures that we remain at the forefront of scientific discovery and therapeutic advancement.

Navigating gynecologic cancers

Featured trials

STATUSRecruitment Complete

Endometrial cancer: GS-US-682-6769

ASCENT-GYN-01: A phase 3 clinical trial evaluating the safety and effectiveness of sacituzumab govitecan in patients with endometrial cancer who have received prior treatment with platinum-based chemotherapy and immunotherapy (GOG-3104/ENGOT-en26).

According to the American Cancer Society, there were about

117,000

new gynecologic
cancer diagnoses

in 2024 in the United States

Source: American Cancer Society

Different types of gynecologic cancers

Gynecologic cancer is a condition where the cells in a woman's reproductive system start to grow uncontrollably.

This can happen in any of the 5 main areas of the female reproductive system:

Sources: Centers for Disease Control and Prevention, Centers for Disease Control and Prevention

What is endometrial cancer?

Endometrial cancer is the most common type of gynecologic cancer in the United States. The number of cases has been rising steadily over the last 10 years. Each year, there was about a 1% increase in endometrial cancers in White women and a 2% to 3% increase among women of all other racial and ethnic groups.

Endometrial cancer is a condition where the cells in the lining of the uterus grow more than they should. The uterus is the part of a woman's body, located in the lower belly area between the hips. Symptoms of endometrial cancer may include abnormal vaginal bleeding or pelvic pain.

Sources: National Cancer Institute, American Cancer Society, Centers for Disease Control and Prevention

What is endometrial cancer?

Risk factors include the following:

Aged 50 years and older
Being a Black woman
Obesity
Having metabolic syndrome or type 2 diabetes
Taking estrogen or tamoxifen
Family history of endometrial, colon, or ovarian cancer

Sources: Centers for Disease Control and Prevention, National Cancer Institute, American Cancer Society

What is ovarian cancer?

Ovarian cancer is commonly diagnosed in women between 55 and 64 years old. White and non-Hispanic American Indian, and Alaska Native women are at a higher risk compared to Black, non-Hispanic Asian/Pacific Islander, and Hispanic women.

Ovarian cancer is a condition where cells in the ovaries, fallopian tubes, or peritoneum start to grow more than they should. Unlike cervical cancer, the cause of most ovarian cancers is unknown. Symptoms of ovarian cancer may include bloating, pain in the pelvic area (between the stomach and thighs), trouble eating or feeling full quickly, or urinary symptoms such as constant need to urinate or frequent urination.

Risk factors include the following:

Family history of the disease
Carrying a BRCA1 or BRCA2 genetic mutation
Being of Eastern European or Ashkenazi Jewish descent
Having endometriosis
Experiencing fertility problems

Sources: American Cancer Society, National Cancer Institute, Centers for Disease Control and Prevention, American Cancer Society, American Cancer Society, American Cancer Society, MedlinePlus

What is ovarian cancer?

What is cervical cancer?

What is cervical cancer?

Cervical cancer is commonly diagnosed in women between 35 and 44 years of age. Black and Native American women have a 65% higher risk of death from cervical cancer compared to White women. Despite a 1.7% annual increase in cases for women aged 30-44 years from years 2012-2019, the 20-24 years age group shows promise with an 11% annual decrease, likely due to the HPV vaccination.

Cervical cancer is a condition where cells in the cervix start to grow more than they should. The main cause is a long-lasting infection with human papillomavirus (HPV). Symptoms of cervical cancer may include abnormal vaginal bleeding, pain in the pelvic area (between the stomach and thighs), or an unusual discharge from the vagina.

Risk factors include the following:

Having an HPV infection

Women get HPV through sexual activity with a partner who has HPV—screening tests and the HPV vaccine help with prevention

Having multiple sexual partners
Having one sexual partner who is high risk (has an HPV infection or many sexual partners)
Smoking
Weakened immune system
Family history of cervical cancer

Sources: Centers for Disease Control and Prevention, American Cancer Society, American Cancer Society, American Cancer Society

More patient support and resources

Patients can find additional help and educational information from the following organizations:

ECANA - The Endometrial Cancer
Action Network for African Americans

SHARE Cancer Support

Facing Our Risk of Cancer Empowered

Cancer Support Community

CancerCare

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